after a looong trial and error session i "disenchanted" it  
 i couldt reproduce it everytime. it works also in 2.2:
-load a track 
-enable quantization
-play track
-stop track
-hit a sampler pad to create a sample
-make sure sampler link is active
-now hit locator -> tracks jump to locator and keeps playing  
 -created sample can be unloaded. is not needed anymore
-as long as sampler link is enabled->"locator play mode" on
if you turn  link off -> "locator play mode" off. 
Dont ask for details  
 Sylvian, now its your part 
 Best regards
Marxon