About cartridges

Yesterday talking with a few djs one of them was telling that almost doesn't matter what cartidge you use if you are using an interface... mixvibes for example. Obviously if the needle is damaged then the interface or souncard won't recieve a good quality signal. But he was saying that it was the same thing using an ortofon concorde or an ortofon concorde gold set.
Someone have the true :P?
Someone have the true :P?