@RoJeC I have the exact same problem...
I installed the driver you mentioned in the link, but my PC still crashes whenever I unplug my U46 (Rev. C)...
I also dont know if my U46 might not work correctly. In Mixvibes (3.4.3) I only have a clean sound on the 1 / 2 Channel. But Channel 3 / 4 are distorted.